ABSTRACT
OBJECTIVE: The study aimed to estimate preoperative Mannan-Binding Lectin (MBL) serum levels in patients assigned for elective colorectal surgeries and to assess its relation with the frequency of postoperative septic complications
Patients & Methods: The study included 30 patients assigned to undergo elective colonic resection anastomosis for varied indications. Preoperative assessment included full general and abdominal examination, laboratory investigations, abdominal ultrasonography examination and colonoscopy & biopsy in cases of colonic cancer. All patients underwent abdominal CT for assessment of tumor location, size and the extent of local spread and nodal status .The study included 10 healthy subjects with cross-matched age and sex and donated blood as a control group. Patients were evaluated daily during their hospital stay for the development of Systemic Inflammatory Response (SIRS), Sepsis< severe sepsis or Septic shock and categorized according to Bone’s criteria into free PO, SIRS and Septic groups. Two blood samples were collected the day prior to (S-0) and the 3rd day after surgery (S-1) for estimation of C-reactive protein (CRP) and MBL levels.
|
