Background: The frequency of obesity and overweight continues to increase significantly and has become one of the most important health problems of the century. Bariatric surgery has been recognized as the most effective treatment of morbid obesity as compared to medical and conservative treatments. The main aim of this study was to compare the outcome of SASI bypass with that of SG in regards weight loss duration, maintenance, failure, cost, time of operation, learning curve and postoperative complications, improvement in comorbidities at 12 months of follow-up. Methods: This prospective randomized clinical study was conducted in General Surgery Department of Benha University Hospital. A total of 40 morbid obese non-sweet eaters’ patients will randomly divided into two equal groups, group I a number of 20 patients will undergo laparoscopic SG and group II of 20 patients will undergo laparoscopic SASI. The study duration of the study ranged from 6-12 months. Results: In the current study, there is no significant difference between the two studied groups regarding 3 months postoperative laboratory parameters. There is a significant difference between the two studied groups regarding TG, LDL, FBS, and HbA1c 6-months postoperative. There is a significant difference between the two studied groups as regard TC, TG, LDL, HDL, FBS, and HbA1c 12-months postoperative. There a significant decrease from preoperative to 12 months postoperative regarding BMI in both groups. There is no significant difference between the two studied groups regarding early complications. There is no significant difference between the two studied groups regarding late complications. Conclusion: Both SASI and LSG procedures were safe and effective in the treatment of morbid obese. Both procedures resulted in significant improvement in BMI, lipid and glycemic profiles. SASI procedure results in better outcome as regard the improvement in both lipid and glycemic profiles, but it was comparable with LSG as regard operative data and rate of early and late complications. Further comparative studies with larger sample size and longer follow-up are needed to confirm our results and to identify risk factors of adverse events. |
