Psoriasis is a mild, persistent, immune-mediated disorder characterised by skin lesions and extracutaneous comorbidities linked to systemic inflammation. Typical psoriasis skin signs involve painful, itchy, and burning plaques that are erythematous, indurated, and scaling. The pathogenesis of psoriasis has been linked to fungi such as Malassezia and Candida albicans. The aim of this research is to look into the connection between psoriasis and the existence of various fungal growths. Patients and Procedures: From April 2019 to July 2020, this research was conducted on a total of 30 patients with psoriasis who attended the outpatient clinic of Benha University Hospital's Dermatology and Andrology Department. To validate the diagnosis, both patients underwent a thorough background taking, general assessment, and dermatologic examination. Before being enrolled in this report, all participants gave their informed consent, which was authorised by the Research Ethics Committee at Faculty of Medicine Benha University. Scales were gently scraped from the lesions and inspected microscopically for any fungal growth using 10% potassium hydroxide (KOH), before being cultured on Sabouraud's Dextrose Agar (SDA) with and without cyclohexamide and Dixon's medium for identification of any fungal growth. The average age of the patients was 38.3, twenty of them were men, and 15 of them were cigarettes. Just seven of the patients have a family history of cancer. The majority of patients saw a slow initiation and progression of exacerbation and remission. Twenty-two psoriasis patients had healthy KOH and fungal development cultures. Aspergillus, Candida, Malassezia, and Dermatophytes were included in ten instances, seven in Candida, four in Malassezia, and one in Dermatophytes. Conclusion: While fungal infection may play a role in the pathogenesis of psoriasis, its occurrence is still a point of contention, and its precise role requires further investigation. |
