The present study aimed to investigate effect of Radish, Cabbage and Jews mallow on lead toxicity in rats. This work was carried out on 48 adult male rats of Sprague Dawely strain. The mean weight of male rats ranged from 110± 5 g. The rats were randomly classified as follows: I- Control group (negative group), which consisted of six rats fed on standard diet and supplied with tap water. II- lead acetate rats group, which included 42 rats fed on standard diet with lead acetate and reclassified into 7 groups ( 6 rats each ) as follows:- 1- Group consumed standard diet with lead acetate( control positive group ). 2 - Group fed on lead acetate diet with 5% dried radish. 3- Group fed on lead acetate diet with 10% dried radish. 4 - Group fed on lead acetate diet with 5% dried cabbage. 5 - Group fed on lead acetate diet with 10% dried cabbage. 6 - Group fed on lead acetate diet with 5% dried Jews mallow.7 - Group fed on lead acetate diet with 10% dried Jews mallow. The duration of the study was six weeks. Results of this study showed that the highest increase in body weight gain showed in group which treated with 10% Radish (3G). While the lowest value in body weight gain was found in the group of rats fed on (5%) cabbage (G5). The highest decrease in serum cholesterol, LDL-c and VLDL-c recorded for the group treated with 10% Jews mallow. The highest decrease in the mean all treated groups with tested diets improved the mean value AST, ALT and The lowest decrease in serum ALT enzyme recorded for the group which treated with 5% cabbage followed by 10% Jews mallow, respectively. While the highest decrease recorded for the group treated with 5% radish. All treated groups with 5% and 10% Radish, Cabbage and Jews mallow decreased the mean value of serum lead significantly, as compared to the positive control group. The highest decrease in serum lead recorded for the group which treated with 10% Jews mallow, followed by the group treated with 10% Cabbage, respectively. |
