Background
Tympanic membrane (TM) perforations can arise from a variety of causes. Major causes
include trauma and middle ear disease. Surgical treatment involves higher costs, more effort,
and surgical risks. Therefore, many investigators have studied topical use of substances to
facilitate TM repair. Estrogen can infl uence the various phases of wound healing in cutaneous
repair. Topical estrogen application may infl uence the repair of TM perforations.
Aim of the work
The aim of the work was to evaluate a new procedure for repairing TM perforation and improving
hearing threshold after 30 days using estrogen paper patch.
Patients and methods
After obtaining informed consent, patients were randomly allocated into two groups. One group
was treated with estrogen paper patch (paper patch impinged with1% estrogen ointment to act
as the study group), and the second group was treated with paper patch impinged with local
antibiotic ointment to act as the control group (we used 1% tetracycline ointment in our study).
Conclusion
Perhaps, there is a signifi cant and promising result for estrogen paper patching as a method
of repairing TM perforation. |
