Background: Preterm labor, accounts for the vast majority
of infant mortality and morbidity. One of perinatal care
primary goals is now the prevention of preterm labor. Aim:
to determine whether vaginal progesterone maintenance
medication could lengthen the latency period following a
successful episode of preterm labor, this study examined
this possibility. Methods: The women were split into two
groups when the uterine contractions stopped: 50 patients
made up the first group (the study group). A micronized
vaginal progesterone supplement
was administered to women daily in doses of 200 mg.
Progesterone vaginal suppository was continued, and the
women were told to reduce their physical activity, until 36
weeks of gestation. There were 50 patients in the second
group (the control group). In addition to being told to
minimize their physical activity, women were not offered
any medicines or follow-up care. Patients were kept in the
hospital if labor pain persisted; otherwise, if they were
stable, they were released. Results: the study discovered
that vaginal progesterone lower the risk of labor before 37
weeks of gestation for women who are more likely to high
risk for preterm labor. Accordingly, treatment with
progesterone agents to lessen preterm birth complications
should continue to women who are at risk. Conclusion: In
this study, it was discovered that preventive treatment of
200 mg vaginal suppositories of progesterone following
successful tocolysis was linked to a longer gestation period
and improved fetal outcomes in high-risk patients. |
