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Dr. Omnia Alsaid Abdallah :: Publications: |
Title: | Serum Level of Growth Arrest–Specific 6 (Gas6)Protein and Genetic Variations in the Gas6 Gene inPatients with Type 2 Diabetes Mellitus |
Authors: | Nehad A Fouad. Sheref M Eltaher, Omminea A Abdullah, Ramy A Metwally |
Year: | 2015 |
Keywords: | Not Available |
Journal: | Not Available |
Volume: | Not Available |
Issue: | Not Available |
Pages: | Not Available |
Publisher: | Not Available |
Local/International: | International |
Paper Link: | Not Available |
Full paper | Omnia Alsaid Abdallah_5-Nehad-Banha2FINAL.pdf |
Supplementary materials | Not Available |
Abstract: |
Growth arrest-specific protein 6 (Gas6) belongs to a family of vitamin K-dependent coagulation proteins. Plasma levels of Gas6 are associated to altered glucose tolerance. This study aimed at determining whether c.843+7G>A Gas6 polymorphism is associated with the development of type 2 diabetes mellitus. The study included 05 patients with type 2 diabetes and 40 matched controls. The Gas6 protein was measured in serum using ELISA and Gas6 gene polymorphism by polymerase chain reaction-Restriction Fragment Length Polymorphism. The GG genotype was the most prevalent in the diabetic patient. The frequency of A allele in the diabetic group was lower than the control group (P |