Fibromyalgia syndrome (FMS) may cause functional disability, severe pain and fatigue and affect quality of life (QOL)which interfere with daily activities of patients. Aim: To examine the association of body mass index (BMI) and symptom severity, QOL and functional capacity in patients with fibromyalgia. Subjects and Methods: Fifty women(50) with fibromyalgia and thirty (30) age matched healthy women control group were subjected to BMI, socio-economic (SES) status assessment and clinical assessment of fibromyalgia by FMS-related measurements, visual analogue scale (VAS), Number of tender points (NTP) Fibromyalgia Impact Questionnaire (FIQ),Myalgic score. The short–form health survey 36, Functional capacity will be assessed by six minute walk test. Results: The majority of patients were obese (74%) distributed as (48%) class 1, (20%) class 2, and (6 %) class 3 .Greater fibromyalgia-related symptoms and functional impairment were found in the higher BMI group with statistically significant differences regarding SES total score; education and culture total domain, NTP and myalgic score,6 minutes' walk test, some domains of SF36 and liptin concentration . Severe FM showed higher VAS, NTP, Myalgic score ,disease duration , BMI and liptin concentration but lower age and SESthan other grades with statistically significant differences regarding disease duration VAS, myalgic score ,liptin concentration and all SF36 domains except general health perception .
Conclusion and Recommendation: The findings support that excess weight is negatively related to QOL, functional capacity ,SES but positively related to disease severity ( clinical and lab ) in women with FMS. A fibromyalgia treatment program needs to incorporate medical and behavioral weight loss programs for obese patients
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