Background
Chronic obstructive pulmonary disease (COPD) is the third leading universal cause of
mortality. Although chronic obstructive pulmonary disorder is primarily a chronic
disease, a great number of patients complain of exacerbations. Severe
exacerbations are associated with worse survival consequences. This study
aimed to detect changes in serum sodium, potassium, and ionized calcium (Na, K,
and ionized Ca) during COPD exacerbation.
Patients and methods
A total of 45 patients with exacerbation of COPD and 15 apparently healthy
participants were included. Serum electrolytes (Na, K, and ionized Ca) were
obtained from patients and controls. Full clinical history, complete blood count,
renal and liver function, serum electrolytes (Na, K, and ionized Ca), and oxygen
saturation measurement were done for patients.
Results
Serum Na, K, and ionized Ca were decreased in patients than controls (with
statistically significant difference). These electrolytes levels were lowest in lifethreatening
exacerbation than other grades of exacerbations (with statistically
significant difference).
Conclusion
COPD exacerbation is associated with low levels of Na, K, and ionized Ca. |
