Background: For clinicians to determine the possibility for
neonate brain damage and guide therapeutic decisions to avoid
long-term complications, as cerebral palsy involving umbilical
artery cord PH, base deficit(BD), and lactic acid, the majority of
biomarkers that are utilized for assessing fetal wellbeing,
neonatal metabolic acidosis, and its associated complications in
newborns are inaccurate and non-specific. On the other hand,
the pH eucap demonstrates that it is the best biomarker and
predictor for newborn metabolic acidosis and the obstacles that
are associated with it. Aim: To evaluate the value of neonatal
cord eucapnic PH in prediction of neonatal intensive care unit
(NICU) admission in newborn subjected to perinatal asphyxia.
Patients and methods: This prospective cohort investigation
conducted on 40 newborns who subjected to perinatal asphyxia
and cord blood pH and eucapnic pH were measured and
correlated with parameters of morbidity and mortality. Results:
there is statistically significant difference between eucapnic pH
and NICU admission; as mean of eucapnic pH was higher
among neonates admitted to NICU (P=0.03). Also ROC analysis
(Receiver operation Curve) showed that eucapnic PH had best
prediction for NICU admission with sensitivity (90.91%) and
specificity (58.62%) at cut-off point (7.03), while umbilical
artery (UA)cord PH had sensitivity (63.64%) and specificity
(55.85%)at cut-off point(6.85). a significant positive correlation
has been detected between UA cord and pH euc-n and between
pH euc-n and UAco2 with(r=0.369, P=0.019). (r=0.789,
P |
