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Dr. Rehab Mohammed Salem :: Publications:

Title:
Predictive value of serum markers for postacne scarring
Authors: El-Taweel AA1, Salem RM1, El-Shimi OS2
Year: 2018
Keywords: acne scarring; acne vulgaris; postacne scarring
Journal: Not Available
Volume: Not Available
Issue: Not Available
Pages: Not Available
Publisher: Wiley Periodicals, Inc.
Local/International: International
Paper Link:
Full paper Rehab Mohammed Salem_Predictive value.pdf
Supplementary materials Not Available
Abstract:

Abstract BACKGROUND: Postacne scarring is the main concern of many acne patients. Predicting the liability to scarring can alter the management protocols and help in preventing such disfigurement. METHODS: Sixty patients with moderate to severe acne vulgaris (according to Global Acne Grading system) were included, only 35 of them had postacne scars. A quantitative latex agglutination commercial kit was used to assess serum C-reactive protein (CRP) concentration by turbidimetry, while serum hepcidin concentration was assessed by a commercially available double-antibody sandwich enzyme-linked immunosorbent assay (ELISA) kit. RESULTS: Patients with postacne scarring had significantly lower serum levels of hepcidin (P-value < .001) and significantly higher serum levels of CRP (P-value < .05). CONCLUSION: Serum levels of hepcidin and CRP are promising markers, which may be considered as objective tools to predict the possibility of postacne scarring.

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