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Dr. Safwa Mahmoud Soror :: Publications: |
|
| Title: | Alchemilla vulgaris modulates
isoproterenol-induced
cardiotoxicity: interplay of
oxidative stress, inflammation,
autophagy, and apoptosis |
| Authors: | Nuha Anajirih1, Ahmed Abdeen2*, Ehab S. Taher3, Afaf Abdelkader4, Hoda A. Abd-Ellatieff5, Mahmoud S. Gewaily6, Nashwa E. Ahmed7, Rasha H. Al-Serwi8, Safwa M. Sorour9 |
| Year: | 2024 |
| Keywords: | Not Available |
| Journal: | Not Available |
| Volume: | Not Available |
| Issue: | Not Available |
| Pages: | Not Available |
| Publisher: | Not Available |
| Local/International: | International |
| Paper Link: | Not Available |
| Full paper | Safwa Mahmoud Soror_fphar-15-1394557.pdf |
| Supplementary materials | Not Available |
| Abstract: |
Isoproterenol (ISO) is regarded as an adrenergic non-selective β agonist. It regulates myocardial contractility and may cause damage to cardiac tissues. Alchemilla vulgaris (AV) is an herbal plant that has garnered considerable attention due to its anti-inflammatory and antioxidant bioactive components. The present investigation assessed the cardioprotective potential of AV towards ISOinduced myocardial damage. Methods: Four groups of mice were utilized: control that received saline, an ISO group (85 mg/kg, S.C.), ISO + AV100, and ISO + AV200 groups (mice received 100 or 200 mg/kg AV orally along with ISO). |
