Background: According to Orem’s definition, self care includes those learned behaviors that individuals perform in order to preserve or promote their daily living activity, health, well being and prevention or treatment of their disease. The aim of this study was to improve daily living activity for clients with Cardiovascular disease using Orem self care theory at Benha City. Design: A quasi-experimental design was used in carrying out this study. Setting the study was conducted at the Medical Outpatients' Clinics of Benha University Hospital and Health Insurance Hospital. The sample of this study included 100 Cardiovascular disease' clients chosen randomly from total (1000). Tools utilized in this study comprised a structured interviewing questionnaire for the assessment of clients' socio-demographic characteristics, knowledge about disease, self-care, and daily living activity, clients' home environment assessment and the health profile for history of Cardiovascular disease' clients; and clients' practices for measuring pulse. Results of this study showed a significant positive effect of self care program on knowledge, practices and self-care of Cardiovascular disease' clients. There were improvements in Cardiovascular disease clients' self-care of daily living activities after conduction of the program. This study concluded that, significant improvement was detected for client's daily living activities after the self care program implementation The study recommended that, Cardiovascular disease clients should be offered continuous refresher home health care programs, promotion and enhancement of the self-care modalities to Cardiovascular disease; written illustrated instructions about disease process, allowed foods, rest and physical activities and follow up should be available at cardiac outpatients' clinics |