Objectives: To assess the value of sequential estimation of biomarkers for prediction of gestation hypertension (GHTN) and preeclampsia (PE) and to stratify PE according to time of development and severity.
Patients & Methods: 80 normotensive (NT) newly pregnant women who continued pregnancy and were free of hypertensive manifestation (NT group), and the GHTN group included 80 newly pregnant NT women who developed high blood pressure (BP) measures without proteinuria after the 20th gestational week (GW). Early-onset PE (EO-PE) was diagnosed if a GHTN woman developed proteinuria before the 34th GW, but after the 34th GW, it is Late-onset PE (LO-PE). PE was diagnosed as mild if BP was |