The toxicological studies of cadmium (Cd), lead (Pb) and manganese (Mn), were carried out on albino rat. Twenty five rat classified to five equal groups. First group was given water contain Cd, Pb and Mn, as (0.54g /L ,0.73g L 0.54g /L)respectively and kept as positive control. Second, third and forth groups were given water (orally by stomach tube 1ml/rat/day for 2 month) contain some pollutant as first group but after treatment with alum, ferric chloride and Pseudomonas bacteria respectively . Fifth group administrated distal water and kept as control negative. At the end of experiment serum sample were collected for estimation of Alanine amino transferase (ALT), Aspatrate amino transferase (AST) and electrolytes (Na, Ca, Ph and K), liver samples collected for determination of oxidative cascade and samples from liver and kidney were collected for residues and histopathological examination. The result indicated that the forth group (given water treated with Pseudomonas bacteria) showed less toxic effect than other groups (second and third) in which water was treated by alum and ferric chloride respectively. We can concluded that removal of heavy metal from water by bacteria was more effective than removal by ferric chloride which was more effective than removal by alum. Key words: Heavy metal, oxidative stress, residues |
