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Dr. Sherif Ibrahim Metwally Ramadan :: Publications: |
Title: | Synthesis of Chondroitin Sulfate A Bearing Syndecan-1 Glycopeptide |
Authors: | Sherif Ramadan, Weizhun Yang, Zeren Zhang, and Xuefei Huang |
Year: | 2017 |
Keywords: | Not Available |
Journal: | Organic Letters |
Volume: | 19 |
Issue: | 18 |
Pages: | 4838-4841 |
Publisher: | American Chemical Society |
Local/International: | International |
Paper Link: | |
Full paper | Not Available |
Supplementary materials | Not Available |
Abstract: |
Syndecan-1 chondroitin sulfate glycopeptide was synthesized for the first time using the cassette approach. The sequence of glycosylation to form the octasaccharide serine cassette was critical. The glycopeptide was successfully assembled via a 2+ (3 + 3) glycosylation strategy followed by peptide chain elongation. |