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Dr. Shuzan Ali Mohammed Ali :: Publications:

Title:
Role of miR-7 as Potential Biomarker for Colorectal Cancer
Authors: Nourhan M.Attia, Amal A.Hassan, Shuzan A.Mohammed, Emad M.Sarhan and Lina A.Mohamed
Year: 2024
Keywords: Colorectal cancer and microRNA-7.
Journal: Benha Journal of Applied Sciences (BJAS)
Volume: 9
Issue: 11
Pages: 73 - 77
Publisher: Benha University
Local/International: Local
Paper Link:
Full paper Shuzan Ali Mohammed Ali_BJAS_Volume 9_Issue 11_Pages 73-77.pdf
Supplementary materials Not Available
Abstract:

Two-thirds of colorectal cancers (CRCs) occur in more developed parts of the world, making it the third most frequent cancer globally after lung and breast cancers. All racial and ethnic groups are affected by CRC, which primarily affects those 50 years of age and older. This condition may arise as a result of a variety of circumstances, including environmental and hereditary ones. The majority of cases are discovered until after symptoms appear, despite the fact that colorectal cancer screening lowers the frequency of diagnosis at advanced stages. MicroRNAs (miRNA), which are frequently dysregulated in cancer, are crucial for regulating gene expression. Since miR-7 affects the expression of several oncogenes, revealing how miR-7 activity is regulated will probably help us better understand the causes of different types of cancer. The purpose of this study was to look at how miR-7 affects colorectal cancer. We discovered a strong correlation between CRC and miR-7. miRNA-7 is circulating as a possible non-invasive biomarker for several illnesses and disorders, including colorectal cancer. This study sought to determine whether microRNA-7 may be used as a diagnostic tool for colorectal cancer

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