This study aimed to evaluate the correlation between serum levels of IL-17 and IL-35 and the presence
and severity of childhood asthma. The study was performed on 60 diagnosed asthmatic children, who
were further classified into four groups according to the Global Initiative for Asthma Guidelines for
Asthma Severity and Control (GINA) 2016, plus 30 age- and sex-matched apparently healthy children.
All participants were subjected to full medical history, clinical examination, pulmonary function tests
and laboratory evaluation in the form of complete blood count (CBC), serum total IgE, IL-17 and IL-35
by ELISA. Our results revealed that eosinophils count, IgE and IL-17 were significantly higher in the
asthmatic group than the control group (p |
