You are in:Home/Publications/Evaluation of lipoarabinomannan in the diagnosis of tuberculosis

Dr. Tarek Samy Abd El Ghany Essawy :: Publications:

Title:
Evaluation of lipoarabinomannan in the diagnosis of tuberculosis
Authors: Ayman A. Youssefa , Mohammed H. Kamela , Hisham A. Eissab , Tarek S. Essawya , Hany H. Moussa
Year: 2017
Keywords: lipoarabinomannan tuberculosis
Journal: Egyptian Journal of Bronchology
Volume: 10
Issue: Not Available
Pages: 291-300
Publisher: Not Available
Local/International: International
Paper Link: Not Available
Full paper Tarek Samy Abd El Ghany Essawy_EgyptJBronchol103291-60701_165140.pdf
Supplementary materials Not Available
Abstract:

Background The detection of lipoarabinomannan (LAM) antigens in body fluids has several potential advantages compared with the diagnostic methods used currently. Aim The aim of this study was to evaluate the possible role of the detection of LAM in the serum and the urine as a diagnostic aid in the diagnosis of different forms of tuberculosis (TB). Patients and methods This study included 62 newly confirmed tuberculosis cases classified into two groups: group A included patients with pulmonary TB (n=36), and was further divided into two groups: group A1 [the smear-positive pulmonary TB group (n=24)] and group A2 [the smearnegative pulmonary TB group (n=12)]; group B included the extrapulmonary TB group (n=26); and 10 apparently healthy individuals served as the control group. The LAM level was measured in the serum and the urine by an enzyme-linked immunosorbant assay. Results The mean level of quantitative serum LAM was higher in group A1 (0.55±0.20?ng/ml) compared with group A2 (0.44±0.30?ng/ml) or group B (0.41±0.27?ng/ml). The mean level of quantitative urine LAM was higher in group A1 (0.81±0.24?ng/ml) compared with group B (0.72±0.35?ng/ml) and group A2 (0.65±0.37?ng/ml; P

Google ScholarAcdemia.eduResearch GateLinkedinFacebookTwitterGoogle PlusYoutubeWordpressInstagramMendeleyZoteroEvernoteORCIDScopus