Prof. Yasser Haroun Mohamed Abo-Essa :: Publications:

البحث الثالث تأثير جهاز الاستئصال المجمع على سقف الفم اللحمي في الأرانب دراسة حجمية و هستولوجية (دراسة تجريبية ) بحث مشترك منشور في مجلة بنها الطبية المجلد 22 العدد 2 مايو 2005 THE EFFECTS OF COBLATION TECHNOLOGY ON THE SOFT PALATE OF RABBITS AN EXPERIMENTAL STUDY Azab Ahmed MD, Yasser Haroon MD , Ismail El-Mofty MD, Mohsen Abd Elrazek MD, and Manal Salman MD*. ENT Department - Benha Faculty of Medicine – Zagazig University. Pathology Department – Ain-Shams University *. Abstract: This study was designed to evaluate the volumetric reduction and the histologic changes of the soft palate after coblation (cold ablation) technology in experimental animals. Sixty male rabbits were included in the study divided into 3 groups : group (A), group(B) and group(C). Each group included 10 control and 10 study animals. Exposure of the soft palate to coblation was done in study animals of the 3 groups submucosaly at 3 sites, one at midportion and 2 at lateral sides of the soft palate for one minute duration in each site. The control animals of the 3 groups were left without any interference. The animals of group A, B and C were studied 1 month, 2 months and 3 months respectively. The soft palate of each rabbit was dissected and volume was calculated. Specimens of soft palate of both control and study animals were examined by electron microscopic study. Died animals were excluded from this study. The comparison of the mean volume of soft palate in the study groups showed gradual increased reduction with time as it was more after 3 months (group C) than 2 months (group B) and 1 month (group A). This result was confirmed by electron microscopic study as there was an increase in the amount of collagen fibers in the subepithelial layer gradually in study groups which was mild, moderate and marked in group A, B and C respectively. Cytoplasmic vacuoles were detected more in the epithelial layer of study group (A) than group (B) this means degenerative changes which is reversible as it was decreased by time and disappeared in group (C). There is no effect on the mucosal glands of the epithelium or underlying muscles. The only histological difference between study and control groups was the increased amount of collagen fibers in the subepithelial layer. Coblation technology could be considered an effective technology for the reduction of the size of soft palate. It is safe , not painful and not invasive as it maintain the normal histology of the soft palate.