This study was carried out on 10 dogs were allotted into two groups, the first included 5 dogs sathjected to experimentally- induced unilateral hydronephrosis, while the second represented by 5 (logs (.Sham Operated dogs) as a surgical control. These dogs were subjected to clinical. haematological and urine examinations. Also Biochemical analysis of serum collected from these dogs was carried out. These dogs were examined ultrasonographically. Also. postmortem and histopathological examinations were carried out on kidneys of necropsied dogs. Results of this study can be summarized as /hllow. Clinical examinations of dogs with surgical unilateral hydronephrosis showed intense lumbar pain at one week then dogs showed no symptoms but the enlarged left kidney could be palpated. lluematological examinations indicated significant increase o/ PCV%, itiBCs and newrophil %. while significant decrease of lymphocyte % and monocyte %. Biochemical analysis of serum of dogs with unilateral hydronephrosis showed significant decrease of albumin, total proteins and sodium, while significant increase of urea and creatinine. Urine examination fear dogs with surgical unilateral hvdronephrosis revealed that urine pll was decreased after 20 clays post- operative. The specific gravity was decreased after Slays post- operation. Protein, Bilirubin and haental¬uria were detected after 5 days post- operative. Ultrasonographic examinations for dogs with surgical unilateral hydronephrosis showed that left kidney size was increased and distended with fluid. Parenchyma became compressed and lost its normal architecture. Post. mortem exam mat on of kidneys revealed dilatation of ureter and enlargement of left kidney that filled with urine. Microscopically revealed cystic dilatation of renal tubules and flattening of their lining epithelium. Also, degeneration of the lining epithelium of some renal tubules with pres-ence of hyaline casts was recorded |
