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Prof. Abdelfattah Monged Selim :: Publications:

Title:
Molecular typing of Coxiella burnetii from Sheep in Egypt
Authors: Abdelfattah Selim; Amir Abdelrahman; Richard Thiéry; Karim Sidi-Boumedine
Year: 2019
Keywords: Coxiella burnetii; Egypt; MLVA; MST; Sheep.
Journal: Comparative Immunology, Microbiology and Infectious Diseases
Volume: 67
Issue: Not Available
Pages: 101353
Publisher: Elsevier
Local/International: International
Paper Link:
Full paper Not Available
Supplementary materials Not Available
Abstract:

Coxiella burnetii, the etiological agent of Q fever, is a globally distributed zoonotic disease. The disease was reported serologically in different animal species and humans in Egypt but the genetic information about circulating Coxiella strains is limited. The present study aimed to genetically characterize Coxiella positive samples, identified in abortive sheep, based on a 17-loci Multiple Locus Variable number tandem repeat analysis (MLVA) panel and Multispacer Sequence Typing (MST). Four MLVA types were found among six examined samples. While all three samples examined by MST were identified as novel sequence type (ST) closely related to human heart valve isolates from France, Saudi Arabia, USA and United Kingdom. This study provides the first genetic information about circulating Coxiella strains in Egypt and improves epidemiological data of Q fever in the country.

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