Background: Diabetic retinopathy is differentiated into two main types. They are non-proliferative andproliferative diabetic retinopathy. The presence or absence of aberrant new blood vessels is the differentiatingcharacteristic between these two groups (retinal or optic disc neovascularization). The ischemic retina secretesvascular endothelial growth factor (VEGF). We conducted a study to evaluate the diabetic changes in the retinain type 1 diabetes mellitus (T1DM) after 15 to 20 years of its diagnosis using Fundus Fluorescein Angiography& Optical Coherence Tomography Angiography & Optical Coherence Tomography. Methods: The study wasdesigned as a retrospective cohort clinical study conducted on T1DM patients. Results & Conclusion: The mostfrequent FFA finding was Microaneurysms (51.7%), followed by Cystoid macular edema (CME) (24.1%), whilethe least frequent findings were an artifact, neovascularization elsewhere (NVE), and branch retinal veinocclusion (BRVO) (3.4% for each). The most frequent OCTA finding was mean FAZ(0.32±0.09mm2) whilemean SVD(46.2±4.6%) while mean DVD (46.1±5.6%).The most frequent OCT finding was epi-retinalmembrane (16.7%), followed by exudate (13.3%) and intraretinal cyst (10.0%), while the least frequent findingwas parafoveal macular edema (3.3%)
(PDF) Evaluation of diabetic changes in the retina in type I diabetes mellitus after 15 to 20 years of its diagnosis. Available from: https://www.researchgate.net/publication/369188146_Evaluation_of_diabetic_changes_in_the_retina_in_type_I_diabetes_mellitus_after_15_to_20_years_of_its_diagnosis [accessed Jul 18 2024]. |