| You are in:Home/Publications/Benzotriazole-mediated alkoxyalkylation and acyloxyalkylation | |
Dr. Bahaa El-Dien M. El-Gendy :: Publications: |
|
| Title: | Benzotriazole-mediated alkoxyalkylation and acyloxyalkylation |
| Authors: | Alan R. Katritzky, Ashraf A.A. Abdel-Fattaha, Krzysztof R. Idzika, , Bahaa El-Dien M. El-Gendya, Jadwiga Soloduchoc |
| Year: | 2007 |
| Keywords: | Not Available |
| Journal: | Not Available |
| Volume: | Not Available |
| Issue: | Not Available |
| Pages: | Not Available |
| Publisher: | Not Available |
| Local/International: | International |
| Paper Link: | |
| Full paper | Not Available |
| Supplementary materials | Not Available |
| Abstract: |
Reactions of readily available and stable 1-(α-alkoxyalkyl)benzotriazoles type 9a,b and 10a–d with a variety of silyl enol ethers 11 or 1,3-dicarbonyl compounds 13 give the expected ketones 12a–l (60–92%), β-keto esters 14a,b (62–67%), and malonates 14c,d (79–88%) in which a tetrahydrofuran or tetrahydropyran moiety has been introduced at the α position. 1-(Benzotriazol-1-yl)alkyl esters 7 are converted by cyanide anion into cyanohydrin esters 15a–i (55–98%). |
