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Dr. Bahaa El-Dien M. El-Gendy :: Publications: |
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| Title: | Tautomerism in drug discovery |
| Authors: | Alan R. Katritzky, C. Dennis Hall, Bahaa El-Dien M. El-Gendy, Bogdan Draghici |
| Year: | 2010 |
| Keywords: | Not Available |
| Journal: | Not Available |
| Volume: | Not Available |
| Issue: | Not Available |
| Pages: | Not Available |
| Publisher: | Not Available |
| Local/International: | International |
| Paper Link: | |
| Full paper | Not Available |
| Supplementary materials | Not Available |
| Abstract: |
The influence of tautomerism on the precise structure of drugs and thus of their potential to interact with biological systems is discussed from thermodynamic and kinetic aspects. The types of tautomerism encountered in the structure of drugs in current use are surveyed together with the effect of pH, solvent polarity, and temperature. |
