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Dr. Mohamed abdel Shafy Mohammady Tabl :: Publications: |
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| Title: | Relationship between sclerostin and coronary tortuosity
in postmenopausal femaleswith non-obstructive coronary artery disease |
| Authors: | Ismail Mohamed Ibrahim a,⁎,1, El-Sayed Mohamed Farag a,1, Mohamed Abd El-Shafy Tabl b,1, Mahmoud Abdelaziz |
| Year: | 2020 |
| Keywords: | Sclerostin Coronary tortuosity Tortuosity score Postmenopausal females |
| Journal: | Not Available |
| Volume: | Not Available |
| Issue: | Not Available |
| Pages: | Not Available |
| Publisher: | Not Available |
| Local/International: | International |
| Paper Link: | Not Available |
| Full paper | Mohamed abdel Shafy Mohammady Tabl_1- relationship between sclerotin.pdf |
| Supplementary materials | Not Available |
| Abstract: |
Background: Coronary tortuosity (CT) is commonly encountered in postmenopausal females and is usually present without obstructive lesions. Circulating sclerostin levels are elevated in postmenopausal females. In view of sclerostin's vasculoprotective effect, we aimed to find possible association between circulating sclerostin and CT. Method: We prospectively enrolled 273 consecutive postmenopausal females with non-obstructive coronary artery disease diagnosed by coronary angiography. Presence and severity (by tortuosity score) of CT as well as serum sclerostin levels were assessed for each patient. Results: Patientswith CT (128, 47% of study group)were significantly older (P650 pg/ml was found to be associatedwith presence of CT (AUC 0.69, 95% CI: 0.61–0.75, P |
