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Prof. Randa Mohamed Ahmed Mostafa :: Publications: |
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| Title: | Interstitial cells of Cajal, the Maestro in health and disease World J Gastroenterol 14,16(26): 3239 – 3248 2010 PMID: 20614479 [PubMed – Indexed for Medline ]. |
| Authors: | Mostafa ,R.M., Moustsfa , Y.M. and Hamdy , H |
| Year: | 2010 |
| Keywords: | Interstitial cells of Cajal; Gastrointestinal motility; Peristalsis |
| Journal: | Not Available |
| Volume: | Not Available |
| Issue: | Not Available |
| Pages: | Not Available |
| Publisher: | Not Available |
| Local/International: | International |
| Paper Link: | Not Available |
| Full paper | Randa Mohamed Ahmed Mustafa_Paper 9 Interstitial cells of Cajal %2c the Maestro in health and disease 2010 World Journal of Gastroenterology.pdf |
| Supplementary materials | Not Available |
| Abstract: |
Interstitial cells of Cajal (ICC) are important players in the symphony of gut motility. They have a very significant physiological role orchestrating the normal peristaltic activity of the digestive system. They are the pacemaker cells in gastrointestinal (GI) muscles. Absence, reduction in number or altered integrity of the ICC network may have a dramatic effect on GI system motility. More understanding of ICC physiology will foster advances in physiology of gut motility which will help in a future breakthrough in the pharmacological interventions to restore normal motor function of GI tract. This mini review describes what is known about the physiologic function and role of ICCs in GI system motility and in a variety of GI system motility disorders. |
