This study was investigating the chemical and physical analysis of bee venom and royal jelly before
and after lyophlization process and found that the lyophlization process improved the efficiency of the enzymes
and active ingredients as a result of low moisture to 5%. The use of bee venom and royal jelly improved the
therapeutic efficiency of some diseases: improving the sexual efficiency, the functions of the kidney and
decrease the rate of glucose by using the doses of 500 mg and 1 gram of (1mg of lyophilized bee venom
+500mg of lyophilized royal jelly +25mg honey) / kg of body weight orally daily for adult male rats for a
month. This study showed that the treatment of adult male rats by 1 gram (1mg of lyophilized bee venom
+500mg of lyophilized royal jelly +25mg honey) / kg of body weight orally alone resulted in increasing the
weights of the testis and the body of the epididymus, sperm count, testosterone hormone, the percentage of live
sperm, and glutathione level, accompanied with decrease in malondialdehyde level and the percentage of sperm
abnormality. The oral administration of (1mg of lyophilized bee venom +500mg of lyophilized royal jelly
+25mg honey) in doses of 500 mg and 1 g/kg body weight today for one month increased urea concentration in
serum and decreased in urine, urea clearance in urine was also decreased as compared to control group. (1mg of
lyophilized bee venom +500mg of lyophilized royal jelly +25mg honey) in a dose of 1 g/kg body weight daily
decreased serum, urine and creatinine levels. Decrease in serum glucose level was also observed when the test
animals were treated with (1mg of lyophilized bee venom +500mg of lyophilized royal jelly +25mg honey) in a
dose of 500mg and 1g /kg body weight daily. Remarkable for one month was showed increasing in body weight
of adult rats that treated with 1g (1mg of lyophilized bee venom +500mg of lyophilized royal jelly +25mg
honey) /kg of body weight compared with control group. This study recommended that using mixtures of
lyophilized bee venom and royal jelly which are dissolved in honey as therapy of sexual efficiency, kidney and
sugar diseases. |