Analyticl Aplication For The Determination Of Aminoglycoide Antipiotics Fiaton-pair Formathion And Their Biological Activies :

Noha Abd Alla Anwar Amir Supervised Ahmed Shalaby

This present thesis comprises four chapters :Chapter 1 includes an introduction and aliterature survey on the method of determination of amikacin sulphate , neomycin sulphate, tobramycin sulphate and vancomycin hydrochlorid. Chapter 2 includes the experimental part , the materials , preparations of the solid ion-pair complexes, solution , instruments determination of the opitimum experimental conditions for ion- pair precipition from aqueous solutions and the quantitative determination of the drug used. Also , this chapter includes the optimum experimental conditions for conductimetric determination, atomic absorption study and spectral measurement of the investigated drugs. The soild ion – pair complexes of the drugs under investigation with ammonium reineckate , potassium ferrocyanide, cobalt thiocyanate, nickal thiocyanate and sodium nitroprusside are confirm by elemental analysis and deterrnination of metal content.