Oropharyngeal Manifestations In Association With Skin Diseases:

Ahmed Mohsen Abdel Fattah Saleit

Several skin diseases are associated with manifes-tations in the oropharynx. The patient may present to the E.N.T. Surgeon before seeking a dermatologist. So it is the duity of the E.N.T. specialist to be acquanted with such manifestations, especially for those diseasesthat give their manifestations first in oropharynx. This thesis have the goal of studying the manifestations of five skin diseases in the region of oropharynx in order to achieve the proper diagnosis and management of such diseases as dealt by the E.N.T. surgeon.Eighty cases of both sex and of different age groups with skin disease showing manifestations in the oropharynx were studied from the clinical, pathological, virological,immunological, and cytological point of view. These skindiseases are:1Pemphigus10 cases2Lichen planus20 cases3Erythema multiforme23 cases4Psoriasis22 cases5Behcet’s disease5 casesFifty cases as a control were selected and investi-gated virologically, immunologically, cytologically.In each of the above diseases the following were done:1.Clinical examination with special emphasis to oropharynx.2.Taking a biopsy from both skin and oral mucosa . The skin biopsies were divided into 2 parts (one for virological study, the other for histopatho-logical and immunofluorescent study) .3.Scraping of the oral cavity or the base of the bullae for cytological examination.from this thesis we conclude that:1.Histopathology was the most important tool for diagnosis of skin lesions.2.Cytological examination was an adjuvant in diagnosis.3.Herpes simplex virus was responsible for the aetiology of some cases of erythema multiforme.