Impact Of Lead On Hearing:

Usama Abd El-baset Hadhoud

Inorganic lead toxicity is a well-known entity. This metallic ement has many applications and is commoiy found in home and dustrial surroundings.This study was carried out to evaluate the toxic effect of lead on e inner ear structure and hearing threshold level.Our epidemiological study was conducted on 1000 Egyptian ,bjects from the suburban of Kalyoubia Governorate that were vided into 2 groups, 500 lead - exposed subjects in their daily job rd 500 controls (sex and age matched) .For all the studied groups -pb level, EPP and HTL were estimated. BAEP was done on 50 posed subjects only. There was statistically significant difference Iween both groups in B-pb level, EPP level in blood and in HTL. ;gated to lead exposed subjects there was a +ve significant rrelation between B-pb level and HTL and there was +ve rrelation between B-pb level, age and duration of exposure to lead. le subgroup (randomly taken from the exposed subjects) that was sted by (BAEP) 4 subjects only from 50 lead - exposed subjects owed prolongation in IPLP (I-V) .In the experimental study that was conducted on 30 guinea pigs 0 guinea pigs poisoned by I .P injection of 1°/0 lead acetate solutio