The Value Of Fibronectin In Bile For The Diagnoosis Of Bile Duct Stricture:

Ramadan Ahmed Ramadan

Fibronctins are high molecular weight extracellular glycoproteins,which are abundant in plasma, but are also found in most other bodyfluids including bile.In our study we selected thirty patients with obstructive jaundice (’1’2 ofthem have benign obstructive jaundice and ’l’2 of them have malignantobstructive jaundice).All patients were subjected to full clinical assessment, laboratorywork, ultrasound and ERCP.During ERCP: brush cytology and bile samples were taken fordetection of fibronectin level.It was found that fibronectin is highly significantly elevated in bile ofpatients with malignant obstructive jaundice, but brush cytology isspecific but non - sensitive test for diagnosis of malignant obstruction