/endometair Bipsy In Infertilty :

Nour Eldin Ibrahim Ashmawy

This work aimed at the study of pathological changes in the endometrium in cases of infertility. The studywas carried on premenstrual endometrial biopsies of 200, successive cases of infertility referred to the DiagnosticCytopathology Unit, Ain Shams University. The study was conducted in an attempt to evaluate the role of endometrial biopsy in diagnosing the cause of infertility. In each case studied, the age, duration of infertility and any available clinical data were recorded and haematoxylinand eosin stained sections were thoroughly reexamined. In 60.5% of cases, the endometrium showed no pathological change. In 39.5% of cases, the cause of the infertility was evident in the endometrium. Endometrium reflecting hormonal disturbances had marked predominance over inflammatory endometrium (32.5% and 7% respectively).Proliferative endometrium was the commonest hormonal disturbance encountered constituting 15% of all cases, followed by luteal phase defects (13%). Of the inflammatory causes, chronic non specific endometritis came first affecting 4.5%. Adhesive endometritis affecting only 0.5%. from this study we concluded that endometrial biopsy in cases of infertility is valuable, firs, in detection of ovulation, secondlyfor evaluating the efficiency of the luteal phase necessary for nidation. Also it is helpful, hyperplasia,inflammations, adhesions or neoplasia which could be the cuase of infertility, can be detected infcause.